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KMID : 1214920190250020110
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Soonchunhyang Medical Science
2019 Volume.25 No. 2 p.110 ~ p.116
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Clinical Usefulness of Neutrophil-Lymphocyte Ratio as a Predictor of Henoch?Schonlein Nephritis
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Kim Min-Sol
Suh Won-Suk
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Abstract
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Objective: Henoch?Schonlein purpura is the most widespread systemic vasculitis during childhood. This study evaluated the relationship between neutrophil-lymphocyte ratio (NLR) and Henoch?Schonlein nephritis, which is important for the long-term prognosis of Henoch?Schonlein purpura.
Method: We retrospectively reviewed patients diagnosed with Henoch?Schonlein purpura at the Department of Pediatrics of Soonchunhyang University Bucheon Hospital between January 2007 and June 2018. One hundred and twelve patients under the age of 18 who were diagnosed with Henoch?Schonlein purpura according to Henoch?Schonlein purpura diagnostic criteria, European League Against Rheumatism were included in the study. Blood and urine test, gastroscopy and colonoscopy, and abdominal computed tomography performed during the first visit were included.
Results: Among 112 Henoch?Schonlein purpura patients, 25 patients were Henoch?Schonlein nephritis. NLR was significantly increased in patients with Henoch?Schonlein nephritis compared to patients without nephritis (P= 0.042), which is an independent predictor of Henoch?Schonlein nephritis.
Conclusion: This study showed that NLR could be a useful predictor of Henoch?Schonlein nephritis in patients with Henoch?Schonlein purpura.
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KEYWORD
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Purpura, Schoenlein-Henoch, Nephritis, Henoch?Schonlein, Neutrophil-lymphocyte ratio
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